Learning Outcomes:
On successful completion of this module students should be able to: - Describe the physiology of gastrointestinal motility.- Describe the physiological regulation of acid and bile secretion.- Describe digestion and absorption in the gut.- Give accounts of nutrition and starvation.- Give an account of gastrointestinal disorders.- Describe the structures and functions of the human kidneys.- Demonstrate understanding of the homeostatic roles sustained by the kidneys.- Use knowledge of the phenomena and mechanisms occurring in the kidneys to explain the performance of their homeostatic functions.- Predict the principal consequences of renal failure of various origins.
Indicative Module Content:
The module content is divided into 50% Gastrointestinal Physiology and 50% Renal Physiology.
Key topics in Gastrointestinal Physiology include:
• Histology of the GIT and its accessory organs
• Salivary glands and swallowing
• Regulation of acid secretion and stomach motility
• Liver physiology bile and jaundice
• Pancreatic secretion
• Small intestine secretions and motility
• Gastrointestinal micro flora and mucosal immunity
• Colon motility and defecation
• Digestion and absorption of key nutrients
• Biochemistry relating to:
o Whole body metabolism
o Obesity
o Metabolism of alcohol
o Vitamins and minerals
Key topics in Renal Physiology include:
• Histology of the kidney and its associated organs
• Renal function and circulation
• Ureters, urinary bladder and micturition
• Renal glomerular filtration and renal clearance
• Renal proximal tubular reabsorption and secretion
• Renal diluting segments and collecting system
• Urinary concentration
• Osmoregulation
• Extracellular fluid volume and sodium balance
• Acid-base physiology