Learning Outcomes:
On successful completion of the module, students should be able to;
1. Discuss the mechanisms, pathological features, and complications associated with cellular adaptation, injury, and death.
2. Describe the aetiology, pathophysiology, and complications of acute and chronic inflammatory responses.
3. Outline the basis of autoimmunity and immunodeficiency, and explain the role of the immune system in transplantation.
4. Outline the main mechanisms by which genetic abnormalities lead to disease.
5. Discuss the pathogenesis and pathological features of benign and malignant neoplastic disease.
6. Outline key pathways of cellular metabolism and their relevance to metabolic disease.
7. Describe the influence of environmental factors on the development and progression of disease.
8. Provide an integrated overview of underlying pathological processes using case-based examples, highlighting their relevance to physiotherapy practice.
Indicative Module Content:
Cellular adaptation, injury and death; innate and adaptive immunity; acute and chronic inflammation; healing and repair; genetic diseases; transplantation and graft-versus-host disease; tumour biology and carcinogenesis; cell metabolism; thrombosis, embolism and infarction; environmental and nutritional pathology; case-based tutorials integrating pathological mechanisms with practice.