PHAR40030 Advanced cardiovascular pharmacology: mechanisms and pharmacotherapy in atherothrombotic disease

Academic Year 2021/2022

This module is core for stage 4 of the BSc (Hons) degree in Pharmacology. The module evaluates existing and potential therapies for disordered haemostasis and atherosclerosis in chronic and acute vascular disease.Topics covered include the cellular and molecular mechanisms in the pathogenesis of atherosclerosis and evaluates inflammatory cells as novel therapeutic targets in the treatment of atherosclerosis. In addition drug treatment of dyslipidemia including the pharmacology of statins is addressed. The module also covers advances in antiplatelet therapies including aspirin resistence, anticoagulants and treatment of coronary vascular injury.

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Curricular information is subject to change

Learning Outcomes:

On completion of this module students should be able to:1. Describe the molecular mechanisms of atherogenesis. 2. Describe the cellular targets for novel therapies 3. Appreciate the role of inflammation in vascular disease4. Discuss disordered haemostasis in the context of potential drug targets. 5. Describe the rationale and use of anti-platelet and anticoagulant drugs.

Indicative Module Content:

This module will provide detailed insight to novel therapies for the treatment of atherosclerosis, hyperlipidemia and thrombosis.
Most recent clinical trial data will be discussed

Student Effort Hours: 
Student Effort Type Hours


Autonomous Student Learning




Approaches to Teaching and Learning:
Lectures, group discussion, review and exam preparations 
Requirements, Exclusions and Recommendations

Not applicable to this module.

Module Requisites and Incompatibles
Not applicable to this module.
Assessment Strategy  
Description Timing Open Book Exam Component Scale Must Pass Component % of Final Grade
Examination: In Semester Exam. This will be scheduled towards the end of the Autumn Trimester Coursework (End of Trimester) No Graded No


Carry forward of passed components
Resit In Terminal Exam
Spring Yes - 2 Hour
Please see Student Jargon Buster for more information about remediation types and timing. 
Feedback Strategy/Strategies

• Feedback individually to students, post-assessment

How will my Feedback be Delivered?

Not yet recorded.

Timetabling information is displayed only for guidance purposes, relates to the current Academic Year only and is subject to change.
Lecture Offering 1 Week(s) - 1, 2, 3, 4 Mon 11:00 - 11:50
Lecture Offering 1 Week(s) - 1, 2, 3, 4 Tues 09:00 - 09:50
Lecture Offering 1 Week(s) - 1, 2, 3, 4 Wed 14:00 - 14:50