PHAR30110 Cardiovascular and Renal Diseases

Academic Year 2023/2024

This module covers the pathogenesis, pathology, and pharmacological treatment of cardiovascular and related renal diseases. Emphasis is also placed on microbiological aspects where appropriate. Specific areas covered include hypertension, atheroma, ischaemic heart disease (angina pectoris and dyslipidemias), thrombosis, myocardial infarction, cardiac failure, cardiac dysrhythmias, valvular heart disease including endocarditis. In renal function and disease, special emphasis will be placed on major disease processes affecting the kidney (glomerular and tubulointerstitial disease), therapeutic uses of diuretics, development of kidney and urinary tract tumours, the pathology of urinary tract infections, mechanisms of nephrotoxicity and drug use in renal failure.We would like to remind all students taking this module that there is an expectancy of 100% attendance for the scheduled tutorials

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Curricular information is subject to change

Learning Outcomes:

When you have completed the Cardiovascular (CVD) and Renal Diseases module, you should be able to:
1.Describe the pathogenesis and pathology of atherosclerosis, ischaemic heart disease and thrombosis.
2.Demonstrate an understanding of genetic and environmental factors that may pre-dispose to CVD
3.Describe the laboratory techniques used in the diagnosis of CVD.
4.Distinguish between clinical signs and symptoms associated with different cardiovascular diseases
5.Describe the mechanisms of action of therapeutic agents used for the treatment and effective managment of CVD. 6.Distinguish between the pharmacological approaches to treatment and prophylaxis of CVD
7.Describe the major disease processes affecting the kidney, including diabetic nephropathy.
8.Describe the therapeutic approach in patients with salt and water (volume) overload, including sites, mechanisms of action and therapeutic uses of diuretics.
9.Describe mechanisms of nephrotoxicity.
10.Characterise the pathology of urinary tract infections.

Student Effort Hours: 
Student Effort Type Hours
Specified Learning Activities


Autonomous Student Learning




Small Group






Approaches to Teaching and Learning:
Online Content
Requirements, Exclusions and Recommendations
Learning Requirements:

Students are required to have a background in human physiology and
biochemistry and to have studied the 'Disease Mechanisms & Pharmacological Principles' (PATH30080) module or a module with equivalent learning outcomes.
They are also required to have studied MDSA20170, MDSA20180 and MDSA20190 or modules with equivalent learning outcomes.

Learning Recommendations:

It is highly recommended that students taking this as an elective module contact the module coordinator to discuss the prior learning requirements.

Module Requisites and Incompatibles
PATH30080 - Disease Mechanisms & Pharmacol

MDSA30200 - GI/GU Illness, PATH30200 - GI/GU Illness, PHAR20020 - Drug action in body systems

Assessment Strategy  
Description Timing Open Book Exam Component Scale Must Pass Component % of Final Grade In Module Component Repeat Offered
Examination: Section B of final exam: Clinical Case #1-related questions 2 hour End of Trimester Exam No Graded No


Examination: Section B of final exam: Clinical Case #2-related questions 2 hour End of Trimester Exam No Graded No


Examination: Section A of final exam: MCQ 2 hour End of Trimester Exam No Graded No



Carry forward of passed components
Resit In Terminal Exam
Autumn Yes - 2 Hour
Please see Student Jargon Buster for more information about remediation types and timing. 
Feedback Strategy/Strategies

• Group/class feedback, post-assessment

How will my Feedback be Delivered?

Not yet recorded.

Name Role
Professor Orina Belton Lecturer / Co-Lecturer
Dr Thomas Crotty Lecturer / Co-Lecturer
Dr Sara Dakir Lecturer / Co-Lecturer
Dr Peter Holloway Lecturer / Co-Lecturer
Dr Simone Marcone Lecturer / Co-Lecturer
Dr Dean Moore Lecturer / Co-Lecturer
Dr Seema Nathwani Lecturer / Co-Lecturer
Dr Patrick Twomey Lecturer / Co-Lecturer
Dr Eoghan O'Connor Tutor
Dr Alexandros Sykaras Tutor
Dr Luisa Weiss Tutor