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Curricular information is subject to change
On successful completion of this module students should: i) be aware of current clinical biomarker measurements - their benefits and limitations - in specific disease areas; ii) understand how new 'omics methods are being applied to the discovery of biomarkers; iii) appreciate the steps involved in progressing new biomarker discoveries to clinical use; iv) be able to critically evaluate the potential of 'omics and other technologies to deliver biomarkers; and, v) understand the challenges faced in delivering new biomarkers for 'personalised medicine'.
Indicative Module Content:Small group lectures/seminars are given to cover: General Introduction to Clinical Biomarkers; Biobanking; Role of biomarkers in disease risk identification and screening; Biomarkers in aiding diagnosis, assessing prognosis and treatment & monitoring; Discovery and Development of Biomarkers: A case study of aspects and issue of Biomarker Validation & Translation into the Clinic; Proteomics & Protein Biomarker Discovery; Making an imprint on tumour diagnostics: the role of Epigenetics, Translation of Prostate Cancer Protein Biomarkers; Imaging Biomarkers: In Vivo Context; Clinical Diagnostics in Practice; Commercialisation of Biomarkers; Principles of Clinical Biomarker Validation; Biomarkers of kidney injury
Tutorials on Preparing a Biomarker Literature Review and Oral Presentations
Student Effort Type | Hours |
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Lectures | 12 |
Seminar (or Webinar) | 2 |
Specified Learning Activities | 6 |
Autonomous Student Learning | 84 |
Total | 104 |
Not applicable to this module.
Description | Timing | Component Scale | % of Final Grade | ||
---|---|---|---|---|---|
Presentation: Students give a short presentation on the subject of their literature review. The presentation is given to the class. | Coursework (End of Trimester) | n/a | Graded | No | 20 |
Assignment: A literature review is prepared on a subject of the student's choice (approved by module co-ordinator). Review format is according to a specific journal's guidelines. | Throughout the Trimester | n/a | Graded | No | 50 |
Assignment: Three questions will be set on various subjects covered in the module. Word count limited essay type answers will be requested. | Coursework (End of Trimester) | n/a | Graded | No | 30 |
Remediation Type | Remediation Timing |
---|---|
In-Module Resit | Prior to relevant Programme Exam Board |
• Feedback individually to students, on an activity or draft prior to summative assessment
• Feedback individually to students, post-assessment
• Group/class feedback, post-assessment
• Peer review activities
Assignment: Post-assessment students are given a copy of the marked up review and given the opportunity for one-to-one feedback. Presentations: Using a series of written guided questions the students review each other's presentations. Collated copies of the individual qualitative peer assessments are provided to each student. At the time of the presentations, peers ask questions on the content of the presentation and are encouraged to give constructive feedback on style and delivery. Continuous Assessment Essays: Following grading, students can request and receive one-to-one feedback on their essay performance,
Name | Role |
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Dr Stephen Lalor | Tutor |