PATH30070 Mechanisms of Disease

Academic Year 2022/2023

The Mechanisms of Disease module forms part of the core curriculum for students of the B.Sc. in Diagnostic Imaging programme.

The module begins by describing basic mechanisms of cellular injury and adaptation, cell death, inflammation and tissue repair. It then sequentially addresses the general pathophysiology of immune disorders, genetic diseases, neoplasia, environmental and nutritional disorders and vascular disease.

Show/hide contentOpenClose All

Curricular information is subject to change

Learning Outcomes:

On successful completion of the module, students should be able to;

1) Discuss the mechanisms, pathological features and complications of cellular adaptation, cell injury and cell death.
2) Describe the aetiology, pathophysiology and complications of acute and chronic inflammatory responses.
3) Using specific examples, outline the basis of autoimmunity and immunodeficiency and describe the role of the immune system in transplantation.
4) Outline the basis by which genetic abnormalities can give rise to disease.
5) Discuss the pathogenesis and pathology of benign and malignant neoplastic disease.
6) Have an insight into the effects of environmental factors on the pathology of disease.
6) Provide an overview of the underlying pathological process ongoing using specific case-based examples of disease and from the perspective of diagnostic imaging.

Indicative Module Content:

Pathology, Mechanisms of disease - Cell injury, Cancer, Inflammation, Genetics

Student Effort Hours: 
Student Effort Type Hours




Autonomous Student Learning




Approaches to Teaching and Learning:
Blended learning 
Requirements, Exclusions and Recommendations
Learning Requirements:

Students are required to have a knowledge of human anatomy,biochemistry and physiology. The academic suitability of such knowledge for this module, in the case of students who are not registered diagnostic imaging students, will be decided by the module coordinator and potential students interested in taking this module as a general elective should discuss this with the module co-ordinator.
Students who are not registered diagnostic imaging students will be required to sign a written commitment to confidentiality relating to patient histories and respective pathological findings.

Learning Exclusions:

This is an incompatible module for registered UCD Medical Students and Biomedical Health and Life Science students.

Module Requisites and Incompatibles
Mechanisms of Disease (Rad) (RDGY30150)

Assessment Strategy  
Description Timing Open Book Exam Component Scale Must Pass Component % of Final Grade
Examination: End of trimester examination
(blended format)
2 hour End of Trimester Exam No Graded No


Assignment: Assignment Varies over the Trimester n/a Graded No


Carry forward of passed components
Resit In Terminal Exam
Autumn Yes - 2 Hour
Please see Student Jargon Buster for more information about remediation types and timing. 
Feedback Strategy/Strategies

• Feedback individually to students, post-assessment

How will my Feedback be Delivered?

Submitted coursework will be annotated by the examiners. Feedback on the examination will be provided on request.

Textbook: "Pathologic Basis of Disease", Robbins & Cotran

By (author) Vinay Kumar , By (author) Abul K. Abbas , By (author) Jon C. Aster

Name Role
Dr Luana Schito Lecturer / Co-Lecturer
Assoc Professor Paula Byrne Tutor
Dr Nicolas Deseez Tutor
Dr Stephen Lalor Tutor
Dr Fiona McGillicuddy Tutor
Professor Cormac Taylor Tutor
Professor Bill Watson Tutor
Timetabling information is displayed only for guidance purposes, relates to the current Academic Year only and is subject to change.
Lecture Offering 1 Week(s) - 25, 32 Tues 09:00 - 09:50
Lecture Offering 1 Week(s) - 20, 21, 22, 23, 24, 29, 30, 31 Tues 09:00 - 10:50
Lecture Offering 1 Week(s) - 29 Wed 09:00 - 10:50
Lecture Offering 1 Week(s) - 22 Wed 10:00 - 10:50
Tutorial Offering 1 Week(s) - 25, 32 Tues 10:00 - 10:50
Tutorial Offering 2 Week(s) - 32 Wed 11:00 - 11:50
Tutorial Offering 2 Week(s) - 26 Wed 12:00 - 12:50
Tutorial Offering 3 Week(s) - 26, 33 Tues 09:00 - 09:50
Tutorial Offering 4 Week(s) - 32 Wed 12:00 - 12:50
Tutorial Offering 4 Week(s) - 26 Wed 13:00 - 13:50
Tutorial Offering 5 Week(s) - 26, 33 Tues 10:00 - 10:50
Tutorial Offering 6 Week(s) - 32 Thurs 11:00 - 11:50
Tutorial Offering 6 Week(s) - 26 Thurs 16:00 - 16:50