PATH30030 Haematology/Immunosuppression

Academic Year 2023/2024

The Haematology and Immunosuppression module outlines:

1. The diseases of the peripheral blood, bone marrow and lymph nodes and their treatment. It also includes the principles of transfusion; the study of infective agents seen in the immunocompromised patient, helminths and infections seen in the returned traveller and their treatment.

2. The clinical presentation and behaviour of these diseases are introduced together with clinicopathological correlation and elementary planning and evaluation of treatment through case based tutorials, lectures and other modalities such as Multidisciplinary Team sessions (MDTs).

3. The purpose of this module is to provide a strong fundamental understanding of the basic principles of Haematology and Immunosuppression as well as promoting critical thinking around core concepts that will be encountered in clinical practice.

4. Through lectures, tutorials, MDTs, formative and summative assessment practices, the module aims to engage and support self-directed and independent student learning promoting the development of safe, confident and competent medical professionals.

We would like to remind all students taking this module that there is an expectancy of full attendance at all deliverables.

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Curricular information is subject to change

Learning Outcomes:

On successful completion of the Haematology and Immunosuppression module students should have:

1. Improved their biomedical knowledge by being able to:

1A. Describe the mechanisms causing anaemia;
1B. Classify haematologic malignancies, describe their natural histories and their effects on patients;
1C. Describe the mechanisms underlying disorders of bleeding and clotting;
1D. Outline the principles of transfusion of blood and blood products;
1E. Describe the infections seen in the immunosuppressed patient and in patients who have recently travelled abroad;
1F. Classify and describe the behaviour of common pathogenic helminths.


2. Improved their clinical skills by being able to:

2A. Formulate a logical approach to diagnosing the cause of anaemia and apply this to the selection of appropriate treatments;
2B. Explain and discuss the approach to treatment of haematologic malignancies and the agents used in their treatment;
2C. Formulate a rational approach to the diagnosis and treatment of disorders of bleeding and clotting;
2D. Formulate an approach to the diagnosis and treatment of infections seen in the immunosuppressed patient and in patients who have recently travelled abroad, and to infection with common pathogenic helminths.

3. Improved their professional and interpersonal skills by:

3A. Participating in group-based interactive tutorials;
3B. Assimilating the professional approach that Haematologists, Medical Microbiologists and Infectious Disease Specialists demonstrate in their clinical illustrations in lectures and case based tutorials.

Indicative Module Content:

Review of haematopoiesis
Anaemia
Leukaemia
Myeloproliferative neoplasms & myelodysplastic syndromes
Lymphoma
Plasma cell dyscrasias, myeloma, amyloidosis
Bleeding & clotting disorders
Transfusion

Infections in the immunocompromised
Herpes viruses
Protozoa
Aspergillus, Candida
HIV/AIDS
Infections in the returned traveller
Malaria
Helminths
Infection control

Student Effort Hours: 
Student Effort Type Hours
Specified Learning Activities

6

Autonomous Student Learning

80

Lectures

24

Tutorial

4

Seminar (or Webinar)

1

Conversation Class

4

Total

119

Approaches to Teaching and Learning:
Lectures
Case-based interactive review sessions
Tutorials (1x2h Haematopathology, 1x2h Med Micro)
MDT - Multidisciplinary team meeting
BMJ online tutorials 
Requirements, Exclusions and Recommendations
Learning Requirements:

Students are required to have a background in human physiology and biochemistry and to have studied
the Mechanisms of Disease (MED) module (PATH30080)
OR a module with equivalent learning outcomes.

They are also required to have studied modules covering haematopoiesis, lymphatic system, blood groups or a module with equivalent learning outcomes.

This elective is only available to Health Science students.

Learning Recommendations:

Students wishing to register for this module as an Elective MUST please contact the Module Coordinator.


Module Requisites and Incompatibles
Required:
MDSA20240 - Micro, Med Genet, Neoplasia, PATH20000 - Biochem,Immunol&Pharmacol, PATH30080 - Disease Mechanisms & Pharmacol

Additional Information:
Students are required to have a background in human physiology and biochemistry and to have studied Mechanisms of Disease (MED) (PATH30080) OR Med Micro, Med Gen and Neoplasia (MDSA20240) AND Biochemistry, Immunology & Pharmacology (PATH20000)

Equivalents:
Haematology/Immunosuppression (MDSA30030)


 
Assessment Strategy  
Description Timing Open Book Exam Component Scale Must Pass Component % of Final Grade In Module Component Repeat Offered
Assignment: Submission of 5 British Medical Journal (BMJ) online tutorials Unspecified n/a Graded No

10

No
Examination: Case-based MCQs 2 hour End of Trimester Exam No Alternative linear conversion grade scale 40% No

36

No
Examination: Case-based SAQs: Haematology 2 hour End of Trimester Exam No Standard conversion grade scale 40% No

27

No
Examination: Case-based SAQs: Med Micro 2 hour End of Trimester Exam No Standard conversion grade scale 40% No

27

No

Carry forward of passed components
No
 
Resit In Terminal Exam
Spring Yes - 2 Hour
Please see Student Jargon Buster for more information about remediation types and timing. 
Feedback Strategy/Strategies

• Online automated feedback
• Self-assessment activities

How will my Feedback be Delivered?

Students will receive feedback online on the BMJ Learning website; they will be awarded a certificate of completion after each of the five modules.

Robbins and Cotran Pathologic Basis of Disease (10th edition)
Sherris Medical Microbiology (7th edition)
Name Role
Dr Melinda Halasz Lecturer / Co-Lecturer