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Curricular information is subject to change
On successful completion of the module students should be able to:
1. Demonstrate a comprehensive understanding of the molecular mechanisms of proteinopathy in neurodegenerative diseases.
2. Discuss in depth the role of protein aggregation and failed protein clearance in neurodegenerative proteinopathies.
3. Critically evaluate recent research findings into the molecula, genetic and cellular disruptions which underpin these disorders.
4. Demonstrate an understanding of the developments in novel therapeutic strategies for neurodegenerative proteinopathies.
Lecture 1: Prion neuroproteinopathies (NO’S)
Lectures 2+3: Alzheimer's disease (GB)
Lecture 4: Developing therapies for neurodegenerative proteinopathies I (NO'S)
Lectures 5+6: Parkinson's disease (GB)
Lectures 7+8 – Huntington protein (NO'S)
Lectures 9+10 – Motor neuron disease (NO'S)
Lecture 11 – Developing therapies for neurodegenerative proteinopathies II (NO'S)
Lecture 12: Tutorial on assessment strategy (NO’S+GB)
|Student Effort Type||Hours|
|Seminar (or Webinar)||
|Autonomous Student Learning||
A basic understanding of biochemistry and cell biology is recommended.
|Resit In||Terminal Exam|
|Spring||Yes - 2 Hour|
• Feedback individually to students, on an activity or draft prior to summative assessment
• Feedback individually to students, post-assessment
• Group/class feedback, post-assessment
You will be invited to submit a draft assessment on which you can receive individual assessment, prior to main exam. Within the tutorial class you will work in groups on sample questions which you will receive feedback on. We aim to have the main essay will be returned to you, graded and with comments, prior to sitting exams for other modules.
|Dr Gary Brennan||Lecturer / Co-Lecturer|
|Dr Niamh O'Sullivan||Lecturer / Co-Lecturer|
|Professor Mike Scott||Lecturer / Co-Lecturer|
|Lecture||Offering 1||Week(s) - 5, 6, 7, 8, 9||Thurs 12:00 - 12:50|
|Lecture||Offering 1||Week(s) - 5, 6, 7, 8, 9||Tues 11:00 - 11:50|
|Lecture||Offering 1||Week(s) - 5, 6, 7, 8, 9||Wed 10:00 - 10:50|