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Curricular information is subject to change
Upon completion of the module, the student will be able to:
- Describe the use of the major classes of biomaterials (e.g. metals / alloys, ceramics / glasses, natural / synthetic / stimuli responsive polymers and composites thereof) in medical device, pharmaceutical, tissue engineering and regenerative medicine sectors.
- Describe the use of cell-derived biomaterials in medical device, pharmaceutical, tissue engineering and regenerative medicine sectors.
- Select appropriate biomaterial(s) and processing method(s) for the development of devices for a specific cell type and/or clinical indication.
- Specify biophysical, biochemical and biological in vitro microenvironment modulators that control cell fate.
- Specify suitable methods for biophysical, biochemical and biological characterisation of implantable medical devices for a specific clinical indication.
- Understand mechanisms involved in implant failure.
- Understand cytotoxicity and biocompatibility issues relating to implantable medical devices.
- Appreciate regulatory requirements in the development of medical devices.
- Appreciate important ethical considerations in different areas of medical device development.
- Appreciate innovation, commercialisation and clinical translation in medical device development.
- Report and disseminate scientific findings.
- Definitions of biomaterials, biocompatibility, advanced therapy medicinal products, personalised medicine, etc.
- Introduction to different classes of biomaterials (ceramics / glasses, metals / alloys, natural / synthetic / stimuli responsive polymers)
- Introduction to bottom-up / top-down nano- and micro- biomaterial processing methods for the development of 2D and 3D devices (e.g. sponges, hydrogels, imprinted substrates, electrospun scaffolds, etc.)
- Introduction to biomaterials characterisation as necessary (e.g. structural, thermal, mechanical, biological properties, including preclinical and clinical assessment)
- Discuss implant failure
- Introduction to cellular systems and discussion on how we can control cell fate
- Introduction to commercialisation, clinical translation and regulatory requirements
- Discussions on ethical issues associated with biomaterials development
- Clinical indications as necessary (e.g. bone, cartilage, tendon, skin, cornea, etc.)
- Industry talk(s)
- Intellectual property management
|Student Effort Type||Hours|
|Seminar (or Webinar)||
|Autonomous Student Learning||
Not applicable to this module.
|Description||Timing||Component Scale||% of Final Grade|
|Assignment: A medical device related assignment||Unspecified||n/a||Graded||No||
|Examination: end of semester examination||Unspecified||No||Graded||No||
|Multiple Choice Questionnaire: x1 multiple choice in class examination associated with the lectures delivered by Prof Dimitrios Zevgolis||Unspecified||n/a||Graded||No||
|Lab Report: A medical device related lab report||Unspecified||n/a||Graded||No||
|Multiple Choice Questionnaire: x1 multiple choice in class examination associated with the lectures delivered by Prof Kenneth Stanton||Unspecified||n/a||Graded||No||
|Resit In||Terminal Exam|
|Summer||Yes - 2 Hour|
• Feedback individually to students, post-assessment
• Group/class feedback, post-assessment
Letter grades and brief comments related to the two written assignments will be provided to students within three weeks of submission deadlines.
|Professor Kenneth Stanton||Lecturer / Co-Lecturer|
|Lecture||Offering 1||Week(s) - 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11||Thurs 13:00 - 13:50|
|Lecture||Offering 1||Week(s) - 12||Thurs 13:00 - 13:50|
|Lecture||Offering 1||Week(s) - Autumn: Odd Weeks||Thurs 17:00 - 17:50|
|Lecture||Offering 1||Week(s) - Autumn: All Weeks||Wed 13:00 - 13:50|