GENE30070 Undergraduate Research 2

Academic Year 2022/2023

This is a computational research-based module, aimed at students with a strong interest in genomics, genetics, microbiology, computational biology and/or bioinformatics. The module follows on from GENE30060, but ti is not necessary to take both. In GENE30070 students will analyse whole genome sequence data, derived from next generation sequencing of yeasts collected from Irish soil, or obtained from other sources. Some of this data will never have been assembled or analysed previously. Students will use computational methods to assemble and annotate genomes, to identify variations such as Single Nucleotide Polymorphisms, and to propose and address research hypotheses. The approaches used and questions posed will be determined by student input. The module will provide training in state-of-the art technologies in genome analysis. Part of the assessment is to write a short scientific paper describing novel results. In previous years, some of these have been accepted for publication in scientific journals.The module therefore provided an opportunity to engage in novel research. No previous coding experience is required, but it could be advantageous (for example, taking GENE30040 or another introductory programming module). Module teaching will be face-to-face where possible, and online where necessary. Students will need their own laptop/computer (not tablet) for the duration of the module. The module will be examined by continuous assessment, including an in-trimester computer-based exam.