Learning Outcomes:
On completion of this module students should be able to: Explain how living cells can extract, transform and utilise energy from their environment. Predict how the mammalian organism reacts to various states of nutrition, which it may be subjected to over a period. Assess the role, mode of action and interaction of various hormones involved in nutrient metabolism.
Indicative Module Content:
Introduction General concepts and key terminology
Enzymes – Nomenclature, action, key factors on enzyme activity, inhibition
Digestion - Ruminant and Monogastric digestion
Metabolism of carbohydrates Glycolysis
Metabolism of carbohydrates – Gluconeogenesis
Glycogen – Formation breakdown and regulation of its metabolism
Regulation of Glucose Metabolism
Structure and function of mitochondria
The citric acid cycle
Oxidative phosphorylation – Electron transport chain
ATP synthesis and energetic considerations
Photosynthesis – Light reactions – Photosystems in plants
Photosynthesis – Calvin cycle
Metabolism of fatty acids – Lipid oxidation
Metabolism of fatty acids – Ketone bodies and their metabolic role
Metabolism of fatty acids – Biosynthesis of a new fatty acid
Lipid transport and role of lipoproteins
Protein degradation and turnover – Amino acids nomencalture and synthesis
Amino acid catabolism
Amino acid biosynthesis
Urea cycle
Role of hormones in regulation of body functions
Metabolic enzymes: Insulin and glucagon
Integration of metabolic pathways – Role of organs –Food intake and starvation