Learning Outcomes:
On completion of this module students should be able to:
1. Understand the basis of getting nucleic acid into cells and for using viruses as vectors for gene delivery and as vaccines
2. Describe the main viral vectors in clinical use and the methods by which they are produced industrially
3. Understand how gene therapies can be used in vivo and ex vivo to modify patient cells including using gene editing tools
4. Discuss the different analytical challenges and technologies associated with viral gene therapy characterisation
5. Understand the mode-of-action of different non-viral gene therapies and RNA-based vaccines
6. Describe the manufacturing processes involved in non-viral therapies and associated analytics