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CHEM41510

Academic Year 2025/2026

Chem Synth of Natural Products (CHEM41510)

Subject:
Chemistry
College:
Science
School:
Chemistry
Level:
4 (Masters)
Credits:
2.5
Module Coordinator:
Assoc Professor Paul Evans
Trimester:
Autumn
Mode of Delivery:
On Campus
Internship Module:
No
How will I be graded?
Letter grades

Curricular information is subject to change.

Develop appreciation of the structural complexity and beauty of molecules found in Nature. Develop an understanding of how these are assembled naturally and then how, in laboratories we can approach their preparation. This will be achieved by the presentation of selected examples and the chemistry involved in the synthesis of the selected examples will be considered in depth.

About this Module

Learning Outcomes:

After participating in this course, learners will have a better appreciation for the discipline: they will have covered the syntheses of a selected group of naturally occurring compounds (belonging to each of the main classes - alkaloids, polyketides, peptides etc.), and will have been exposed to a range of different chemical reactions. They will better appreciate the motivations behind these syntheses and be able to demonstrate these skills both by answering questions related to specific parts of syntheses and by analysing published syntheses. Ultimately this knowledge will be geared towards the learner being able to design their own, novel, approaches to the chemical syntheses of natural products.

Indicative Module Content:

This module will be delivered in six sessions which will be timetabled for 2 hours. Roughly these will be broken down into the following:

Class 1: Introduction to Natural Products and their Synthesis
Class 2: Selectivity in Synthesis
Class 3: Selected Syntheses of Fatty Acids and Polyketides
Class 4: Selected Syntheses of Oligopeptides and use of Amino Acids in Synthesis
Class 5: Selected Syntheses of Alkaloids
Class 6: Summary and In-Class Asssessment

During each class time will be scheduled in order to complete short problems associated with the material presented.

Student Effort Hours:
Student Effort Type Hours
Lectures

10

Specified Learning Activities

2

Autonomous Student Learning

45

Total

57


Approaches to Teaching and Learning:
The module will be delivered in a traditional face-to-face setting. Notes to support student learning will be supplied and the timetabled sessions will be broken into sections where students can receive information and then practice these ideas using problems supplied. Students will complete some of these individually but also work in small groups. Assessments, in order to judge whether, and to what extent, the student has met the learning objectives, will be built into the aforementioned classroom activities and also will come in the form of set homework assignments.

Requirements, Exclusions and Recommendations

Not applicable to this module.


Module Requisites and Incompatibles
Not applicable to this module.
 

Assessment Strategy
Description Timing Component Scale Must Pass Component % of Final Grade In Module Component Repeat Offered
Exam (Online): A Brightspace-based exam session will be held in-class at the end of the module. This will contribute to half the overall grade. Week 9 Standard conversion grade scale 40% No
50
No
Individual Project: Recorded powerpoint presentation on a research paper. Week 12 Graded No
50
No

Carry forward of passed components
No
 

Resit In Terminal Exam
Spring No
Please see Student Jargon Buster for more information about remediation types and timing. 

Feedback Strategy/Strategies

• Feedback individually to students, post-assessment

How will my Feedback be Delivered?

The Brightspace assessment will be marked automatically and the results triggerred to appear when the assessment period elapses. The recorded powerpoint presentation will be graded and this, and additioanl feedback given individually to each student.

Notes will be provided and these will containg literature references for the primary research papers.

Additionally, the Classics in Total Synthesis books by K. C. Nicolaou and colleagues are recommended.

(James Joyce 547.70459)

Timetabling information is displayed only for guidance purposes, relates to the current Academic Year only and is subject to change.
Autumn Lecture Offering 1 Week(s) - 4, 5, 6, 7, 8, 9 Fri 16:00 - 17:50