Learning Outcomes:
a) describe the applications of Pd-catalysis to modern organic synthesis;
b) outline catalytic cycles for the full range of Pd-catalysed couplings (Heck reaction, cross-couplings, arly aminations and ether formations, CO insertions and allylic substitutions;
c) understand the applications and mechanisms of ring closing metathesis, ring opening metathesis and their use in synthetic chemistry;
d) outline selectivity for the formation of linear aldehydes in hydroformylation reactions,
e) describe the development of asymmetric organocatalysis, with an emphasis on iminium ion and enamine chamistry