CHEM40060 Methods in Organic Synthesis

Academic Year 2024/2025

The module consists of three parts united around the theme of organic synthetic methodology. One part is a systematic introduction to the use of the principles and application of retrosynthetic analysis. The second is a course on the use of protecting groups in the synthesis of multifunctional compounds, using carbohydrates as examples. The third component is an introduction to modern methods for the synthesis of targets in enantiomerically pure form. A problem-solving approach, reinforced by extensive use of tutorial problems, will be used throughout the module.

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Curricular information is subject to change

Learning Outcomes:

On completion of this module students should be able to: (i) devise, and evaluate, synthetic routes to hydrocarbons and to mono and difunctionalised target compounds, (ii) demonstrate an understanding of the use of protecting groups in synthesis, especially in the context of carbohydrates, and (iii) demonstrate familiarity with the principles and methods of enantioselective synthesis, and devise synthetic routes to enantioenriched target compounds

Student Effort Hours: 
Student Effort Type Hours




Specified Learning Activities


Autonomous Student Learning




Approaches to Teaching and Learning:
Lectures, including in-class problem solving.
Independent learning in advance of problem-solving workshops. 
Requirements, Exclusions and Recommendations
Learning Requirements:

This module is intended for students in the final year of an Honours Chemistry degree program or post graduate students in a Chemical discipline. Other students wishing to take this module must have a comparable background in chemistry and must consult the School.

Module Requisites and Incompatibles
CHEM40750 - Org Synthesis 1, taught MSc

Assessment Strategy  
Description Timing Open Book Exam Component Scale Must Pass Component % of Final Grade

Not yet recorded.

Carry forward of passed components
Resit In Terminal Exam
Summer Yes - 2 Hour
Please see Student Jargon Buster for more information about remediation types and timing. 
Feedback Strategy/Strategies

• Feedback individually to students, post-assessment
• Group/class feedback, post-assessment

How will my Feedback be Delivered?

Feedback on homework assignments will be provided in the tutorials. Whole class and group feedback will be provided after the online quizzes and workshop problems.

Name Role
Assoc Professor Paul Evans Lecturer / Co-Lecturer
Professor Declan Gilheany Lecturer / Co-Lecturer
Professor Patrick Guiry Lecturer / Co-Lecturer
Dr Xiangming Zhu Lecturer / Co-Lecturer