Learning Outcomes:
By the end of this module, you will should be able to:
1. Compare and contrast the relative properties of main group elements and predict outcomes of their reactions with hydrogen, oxygen, water and halogens
2. Use Lewis structures and the Valence Shell Electron Pair Repulsion Theory (VSEPR) to predict and explain molecular shapes
3. Draw the unit cells of solid state structures of selected elements, ionic, molecular and network solids, and comment on the nature of alloys
4. Calculate coordination number, formula units per unit cell, symmetry and stoichiometry of simple solid state structures (A, AB, AB2 and AB3 systems)
5. Appreciate the relevance of several examples of main group compounds, metals and transition metal complexes to medicine and biology
6. Predict the stoichiometry, shape and selected properties of coordination complexes from the nature of the central ion and the ligand involved
Indicative Module Content:
The module will have three major sections: Main Group Chemistry, Solid State Chemistry and Transition Metal Chemistry, as well as highlighting numerous applications of the presented chemistry to biological and/or medicinal topics. Indicative content within each section is as follows:
Main group chemistry: Classifying the elements (metals, semimetals and nonmetals); predicting molecular shape using valence electron pair repulsion model; survey of the reactivity and properties of s- and p-block elements, including their reactions with hydrogen, oxygen, water and halogens; allotropes of main group elements and their properties.
Solid state chemistry: Crystalline and amorphous solids; detailed discussion of cubic unit cells and examples of metallic, ionic, network and molecular solids; Bravais lattices; packing efficiency in the solid state; calculation of density and particle radius from solid state structure; interstitial sites, AB and AB2 binary solids and AB3 ternary structures (rock salt, zinc blende, rutile, fluorite, etc); solid-state of carbon allotropes; solid state defects, including semiconductors and alloys.
Transition metal chemistry: d-orbitals and ground state electronic configuration of transition metals, lanthanides and their ions; oxidation states of transition metals; binary compounds of transition metals and reactivity; coordination chemistry, ligands (charge, denticity, macrocycles), nomenclature; coordination number and coordination geometry; crystal field theory, and impact on colour and magnetic properties (spectrochemical series, high- and low-spin complexes).