Explore UCD

UCD Home >

CELB40190

Academic Year 2024/2025

Advanced Cancer Cell Biology and Genetics (CELB40190)

Subject:
Cell Biology
College:
Science
School:
Biology & Environment Science
Level:
4 (Masters)
Credits:
5
Module Coordinator:
Dr Simone Marcone
Trimester:
Autumn
Mode of Delivery:
On Campus
Internship Module:
No
How will I be graded?
Letter grades

Curricular information is subject to change.

This module covers advanced topics in the biology and genetics of cancer. Topics covered include the hallmarks of cancer, cancer epigenetics, cancer genomics, angiogenesis, invasion and metastases. Recent advances in targeted therapies will also be discussed. Students will have the opportunity to choose one "hot topic" to focus on in a workshop.

About this Module

Learning Outcomes:

On completion of this module, students should be able to:
1. Demonstrate an understanding of the universal hallmarks in the molecular pathogenesis of cancer.
2. Contrast the incidence and mortality of cancers from the developed and developing worlds.
3. Interpret modern research methodologies in cancer biology and genetics.
4. Critically evaluate research findings in cancer biology and genetics.
5. Discuss how discoveries in cancer research are advancing cancer medicine to impact patient care and survival across different parts of the world.
6. Recognise the potential impact of the environment and life choices on cancer development.
7.Identify research leaders in cancer cell biology and genetics from across the world.

Indicative Module Content:

1. The fundamental hallmarks of cancer: an overview
2. Cancer development: role of tumour suppressors & oncogenes
3. Cancer progression: angiogenesis, invasion & metastasis
4. Cancer genomics
5. Cancer epigenetics & epigenomics
6. The dark matter of cancer development: role of ncRNAs
7. Tumour microenvironment & heterogeneity
8. Altered signalling pathways in cancers of the developing & developed world
9. Liquid biopsies: circulating tumour cells, microvesicles & cell-free nucleic acids in cancer detection & management
10. The biology & genetics of cervical cancer
11. The biology & genetics of prostate cancer
12. Breakthroughs in cancer research in the developing & developed world

Student Effort Hours:
Student Effort Type Hours
Specified Learning Activities

10
Autonomous Student Learning

100
Lectures

12
Tutorial

3
Total

125

Approaches to Teaching and Learning:
A mixture of in class and recorded lectures. peer and group discussions, problem-based learning, Cancer Cell webinars

Requirements, Exclusions and Recommendations
Learning Recommendations:

Students should have a good understanding of cell biology and genetics.


Module Requisites and Incompatibles
Not applicable to this module.
 

Assessment Strategy
Description Timing Component Scale Must Pass Component % of Final Grade In Module Component Repeat Offered
Exam (In-person): Examination: End of trimester examination consisting of both short answer and essay style questions End of trimester
Duration:
2 hr(s)
 Graded No
80
 No
Assignment(Including Essay): Assignment: Students choose a webinar to view and write a short blog post. Week 5 Graded No
20
 No

Carry forward of passed components
Yes
 

Resit In Terminal Exam
Spring Yes - 2 Hour
Please see Student Jargon Buster for more information about remediation types and timing. 

Feedback Strategy/Strategies

• Feedback individually to students, post-assessment

How will my Feedback be Delivered?

Not yet recorded.

The Biology of Cancer, 2nd Ed
Robert A. Weinberg

Name Role
Dr Simone Marcone Lecturer / Co-Lecturer

Timetabling information is displayed only for guidance purposes, relates to the current Academic Year only and is subject to change.
Autumn Lecture Offering 1 Week(s) - 1, 2, 3, 4 Mon 12:00 - 13:50
Autumn Lecture Offering 1 Week(s) - 1, 2, 3, 4 Thurs 14:00 - 14:50
Autumn Lecture extra session Offering 1 Week(s) - 12 Tues 09:00 - 09:50
Autumn Lecture Offering 1 Week(s) - 1 Wed 11:00 - 11:50
Autumn Lecture Offering 1 Week(s) - 2, 3, 4 Wed 11:00 - 11:50
Print this page
Fill in the following details:
Enter the body of your query here.

From time to time UCD would like to send you further information that we feel, based on your enquiry, would be of interest to you.