Learning Outcomes:
At the end of this module, the student will be able to:
Discuss innate immunity, including innate recognition of antigens and PRRs.
Describe trained immunity
Discuss immunometabolism
Demonstrate an understanding of inflammatory diseases and recent advances in therapies for these conditions
Compare IgE -mediated allergic disease with non-IgE mediated allergic disease.
Discuss immunodeficiency and immunodeficiency diseases
Describe how pathogens can evade or subvert the immune system
Cite several case studies of chronic inflammatory diseases.
Discuss specific examples of T-cell exhaustion
Discuss current research topics in the field of immunology
Indicative Module Content:
Topics will include innate immunity, innate recognition of antigens, pattern recognition receptors (including cytosolic PRRs) and their signalling pathways; cross presentation; trained immunity, immunometabolism, T-cell subsets, T-cell exhaustion; inflammation and its role in chronic conditions such as Asthma; regulation of the immune system; host directed therapy; vaccines and adjuvants.