BMOL40410 Advanced Immunology

Academic Year 2024/2025

This module builds on the material covered in Stage 3 Immunology module (BMOL30090) and will draw on current research in this rapidly changing field. All contributors have a research interest in immunology and/or inflammatory conditions. Topics will include innate immunity, innate recognition of antigens, pattern recognition receptors (including cytosolic PRRs) and their signalling pathways; cross presentation; trained immunity, immunometabolism, T-cell subsets, T-cell exhaustion; inflammation and its role in chronic conditions such as Asthma; regulation of the immune system; host directed therapy; vaccines and adjuvants.

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Curricular information is subject to change

Learning Outcomes:

At the end of this module, the student will be able to:
Discuss innate immunity, including innate recognition of antigens and PRRs.
Describe trained immunity
Discuss immunometabolism
Demonstrate an understanding of inflammatory diseases and recent advances in therapies for these conditions
Compare IgE -mediated allergic disease with non-IgE mediated allergic disease.
Discuss immunodeficiency and immunodeficiency diseases
Describe how pathogens can evade or subvert the immune system
Cite several case studies of chronic inflammatory diseases.
Discuss specific examples of T-cell exhaustion
Discuss current research topics in the field of immunology

Indicative Module Content:

Topics will include innate immunity, innate recognition of antigens, pattern recognition receptors (including cytosolic PRRs) and their signalling pathways; cross presentation; trained immunity, immunometabolism, T-cell subsets, T-cell exhaustion; inflammation and its role in chronic conditions such as Asthma; regulation of the immune system; host directed therapy; vaccines and adjuvants.

Student Effort Hours: 
Student Effort Type Hours
Lectures

12
Autonomous Student Learning

90
Total

102
Approaches to Teaching and Learning:
Lectures; critical writing; reflective learning; enquiry & problem-based learning; debates; case-based learning; student presentations 
Requirements, Exclusions and Recommendations

Not applicable to this module.


Module Requisites and Incompatibles
Not applicable to this module.
 
Assessment Strategy  
Description Timing Open Book Exam Component Scale Must Pass Component % of Final Grade
Exam (In-person): Mid-trimester Exam/assignment n/a Graded No

30
Exam (In-person): End of trimester exam n/a Graded No

70

Carry forward of passed components
Yes
 
Resit In Terminal Exam
Spring Yes - 2 Hour
Please see Student Jargon Buster for more information about remediation types and timing. 
Feedback Strategy/Strategies

• Feedback individually to students, post-assessment
• Online automated feedback

How will my Feedback be Delivered?

Not yet recorded.