Learning Outcomes:
On completion of this module students should have a deep systems level understanding of the integrated nature of cellular functions that support the establishment and maintenance of health in livestock.
Students should be able to:
1. Explain the concept of homeostasis, and understand how it is established and maintained (including the role of the lymphatic system)
2. Describe the role of nutrient metabolism in cell growth and immune function (including the role of the endocrine system in growth)
3. Appreciate the role of the microbiome in health and disease
4. Understand the relevance of the evolution of the immune system and how the physiology of modern livestock has changed
5. Discuss specific properties and functions of the cells and major molecular components of the immune system, as well as elaborate the process of inflammation
6. Explain the relevance of systemic and local immunity to livestock diseases of relevance
7. Discuss the differences between innate and adaptive immunity and explain the principle concepts of vaccination.
Indicative Module Content:
1. Introduction to homeostasis and it's relevance across physiological systems and in relation to resilience
2. Endocrinology - hormone signaling and mechanisms of action
3. Growth physiology and nutrient partitioning
4. Lactation physiology
5. Evolution of the immune system and how selection pressures have influenced the physiology of modern livestock
6. Cellular and molecular components of the innate and adaptive immune system
7. Mucosal immunity
8. Ontogeny and lifetime immunity (including critical periods like weaning and in the transition cow)
9. Inflammation, vaccination and pathobiology