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Curricular information is subject to change
On successful completion of this module students should:
i) be aware of current clinical biomarker measurements - their benefits and limitations - in specific disease areas;
ii) understand how new 'omics methods are being applied to the discovery of biomarkers;
iii) appreciate the steps involved in progressing new biomarker discoveries to clinical use;
iv) be able to critically evaluate the potential of 'omics and other technologies to deliver biomarkers;
v) understand the challenges faced in delivering new biomarkers for 'personalised medicine'.
Small group lectures/seminars are given to cover: General Introduction to Clinical Biomarkers; Biobanking; Role of biomarkers in disease risk identification and screening; Biomarkers in aiding diagnosis, assessing prognosis and treatment & monitoring; Discovery and Development of Biomarkers: A case study of aspects and issue of Biomarker Validation & Translation into the Clinic; Proteomics & Protein Biomarker Discovery; Making an imprint on tumour diagnostics: the role of Epigenetics, Translation of Prostate Cancer Protein Biomarkers; Imaging Biomarkers: In Vivo Context; Clinical Diagnostics in Practice; Commercialisation of Biomarkers; Principles of Clinical Biomarker Validation;
Student Effort Type | Hours |
---|---|
Autonomous Student Learning | 90 |
Lectures | 15 |
Seminar (or Webinar) | 9 |
Total | 114 |
Not applicable to this module.
Description | Timing | Component Scale | % of Final Grade | |||
---|---|---|---|---|---|---|
Assignment: A critical review of three papers on biomarkers for a specific disease. The papers are identified by the student in line with their area of interest or research project. | Throughout the Trimester | n/a | Graded | No | 40 |
No |
Presentation: Students give a 10 minute presentation on their critical review of the three papers they had selected. The presentation is given to the class. | Coursework (End of Trimester) | n/a | Graded | No | 30 |
No |
Examination: Three questions will be set on various subjects covered in the module. | 1 hour End of Trimester Exam | No | Graded | No | 30 |
No |
Remediation Type | Remediation Timing |
---|---|
In-Module Resit | Prior to relevant Programme Exam Board |
• Feedback individually to students, post-assessment
• Group/class feedback, post-assessment
Critical review Assignment: Post-assessment students are given written feedback of their critical review. Presentations: Post-assessment students are given written feedback on their presentation. Exit examination: Following grading, students can request and receive feedback on their essay answer.
Name | Role |
---|---|
Professor Amanda McCann | Lecturer / Co-Lecturer |
Dr Stephen Lalor | Tutor |