Upon completion of the module, the student will be able to:
 Describe the use of the major classes of materials (e.g. metals / alloys, ceramics / glasses, natural / synthetic / stimuli responsive polymers and composites thereof) in medical device, pharmaceutical, tissue engineering, regenerative medicine, cell culture technologies sectors.
 Select appropriate biomaterial(s) and processing method(s) for the development of devices for a specific cell type and/or clinical indication.
 Specify suitable methods for biophysical, biochemical and biological characterisation of implantable medical devices / advanced therapy medicinal products / cell culture technologies products for a specific clinical indication.
 Understand cytotoxicity and biocompatibility issues relating to implantable medical devices.
 Appreciate regulatory requirements in the development of medical devices.
 Appreciate important ethical, equality, diversity and inclusion considerations in different areas of biomaterials / medical device / tissue engineering / regenerative medicine sectors.
 Appreciate innovation, commercialisation and clinical translation in medical device development.
 Appreciate sustainability concepts (e.g. environmental impact, resource efficiency, circular economy, life-cycle cost) in the biomaterials / medical device / tissue engineering / regenerative medicine sectors.
 Appreciate UN Sustainable Development Goals relevant to biomaterials / medical device / tissue engineering / regenerative medicine sectors.
 Demonstrate knowledge and understanding of the mathematics, sciences, data science, analytics and other technologies underpinning biomedical engineering.
 Appreciate and demonstrate knowledge of engineering management principles (e.g. ability to put together an appropriate experimental design for a medical device / advanced therapy medicinal product / cell culture substrate, taking into consideration relevant regulatory requirements, financial implications, sustainability considerations, ethical aspects, etc.)
 Report scientific findings.

 Definitions of biomaterials, biocompatibility, advanced therapy medicinal products.
 Introduction to different classes of biomaterials.
 Introduction to bottom-up or top-down and nano or micro biomaterial processing methods.
 Introduction to biomaterials characterisation.
 Discussion on implant failure.
 Introduction to cellular systems and discussion on how we can control cell fate.
 Introduction to commercialisation, clinical translation and regulatory requirements.
 Discussion on ethical issues associated with biomaterials development.
 Designing biomaterials and advanced therapy medicinal products for specific indications.
 Designing clinical-indication specific experiments.
 Data analysis and report writing.
 Invited talks.

Not applicable to this module.

• Feedback individually to students, post-assessment
• Group/class feedback, post-assessment
• Online automated feedback
• Peer review activities
• Self-assessment activities

Letter grades and brief comments related to the two written assignments will be provided to students within three weeks of submission deadlines.