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CHEM41470

Academic Year 2024/2025

Modern Mass Spectrometry (CHEM41470)

Subject:
Chemistry
College:
Science
School:
Chemistry
Level:
4 (Masters)
Credits:
5
Module Coordinator:
Assoc Professor Paul Evans
Trimester:
Autumn
Mode of Delivery:
Blended
Internship Module:
No
How will I be graded?
Letter grades

Curricular information is subject to change.

Mass Spectrometry has become an essential analytical technique in life-sciences, forensics and even in aerospace research. In this course, the students will learn the principles of various mass spectrometry techniques that currently exist and their applications. In particular, the module will highlight the applications of mass spectrometry in drug discovery, natural products, and protein science. The students will get deeper understanding of the common terminologies used in mass spectrometry and other associated separation techniques such as liquid chromatography and gas chromatography. They will have hands-on experiments in elucidating the different classes of compounds with various ionisation methods that are routine in a chemical or biochemical science labs. The course will present the development of the hyphenated mass spectrometry methods that has revolutionised the analytical science in terms of throughput, sensitivity and specificity.

About this Module

Learning Outcomes:

On completion of this module students should have in-depth understanding of Mass Spectrometry, its principles and their application. The students should also be able to approach the best Mass Spectrometric techniques for various classes of compounds to elucidate their structures and composition in a given matrix.

Indicative Module Content:

A range of modern mass spectrometry instrumentation and techniques will be covered. These include LCMS (quadrapoles, TOF and orbitrap), GCMS (EI and CI) and other techniques such as MALDI, ion mobility etc.

Student Effort Hours:
Student Effort Type Hours
Lectures

16
Seminar (or Webinar)

4
Laboratories

4
Specified Learning Activities

20
Autonomous Student Learning

56
Total

100

Approaches to Teaching and Learning:
This module is delivered by professional Mass Spectrometrists and covers both theoretical and practical aspects of this important technique. The small class size will suit an interactive approach to covering the material and the assignments will support understanding. The access to the Mass Spectrometry equipment in the School of Chemistry will enable students to gain hands-on experience of the instruments themselves.

Requirements, Exclusions and Recommendations
Learning Requirements:

A basic understanding of the use of analytical methods, as applied to the Chemical Sciences, will be required.


Module Requisites and Incompatibles
Not applicable to this module.
 

Assessment Strategy  
Description Timing Component Scale Must Pass Component % of Final Grade In Module Component Repeat Offered

Not yet recorded.

Carry forward of passed components
Yes
 

Resit In Terminal Exam
Summer No
Please see Student Jargon Buster for more information about remediation types and timing. 

Feedback Strategy/Strategies

• Feedback individually to students, post-assessment
• Group/class feedback, post-assessment

How will my Feedback be Delivered?

Not yet recorded.

Name Role
Dr Jimmy Muldoon Lecturer / Co-Lecturer
Dilip Rai Lecturer / Co-Lecturer
Dr Dilip Kumar Rai Lecturer / Co-Lecturer
Dr Dilip Rai Lecturer / Co-Lecturer
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