Learning Outcomes:
Knowledge and understanding of:
• the principles of organic chemical reactivity, its measurement and the mechanisms of biological reactions;
• the different types of pericylic reactions and the range of reactivity that can be measured by kinetic and other mechanistics investigation
• photochemistry including photocatalysis
• the different types of nitrogen functionality and how their structure leads to different types of chemistry including bonding concepts using the valence bond model and basicity;
• the formation of amines, imines and enamines; their various rearrangements and cycloaddition reactions and a review of amino protection;
• modern synthesis technologies such as microwave and flow chemistry, immobilised reagents, catalysts and scavengers.
• sustainable chemical processes that improve on current practices and the integration of flow chemistry for the synthesis of drug-like target structures.